The Cancer Therapy Institute of the University of Bradford in the United Kingdom recently announced that it has made breakthrough progress in related fields. The researchers transformed colchicine into a smart bomb, specifically attacking tumor cells, inhibiting their growth or killing them completely, while harmless to normal cells.
Colchicine has been widely used in the history of treating inflammation. It has the ability to inhibit cell division, so some people have tried to use it for anti-cancer and anti-cancer, but due to its high toxicity, it will damage human health cells indiscriminately, making it unable to be effectively applied.
Researchers at Bradford used molecular biology techniques to modify the signal response system of colchicine in the cell, adding a protein that makes it inactive in the normal body and is not activated until it reaches tumor cells , Attack the tumor vascular cells to achieve the effect of starving the tumor. The cell signal used to activate the colchicine smart bomb is an enzyme produced by tumor cells. Normally, this enzyme will inhibit surrounding healthy cells so that the tumor can grow. Once the modified protein on the smart bomb meets this enzyme, it will be broken down, which activates the colchicine molecule, inhibits the division of tumor vascular cells, and thus has the effect of destroying the tumor.
Because of this selective recognition mechanism, smart bombs can effectively treat cancer, but there are few side effects of the general colchicine treatment program.
The mouse experiment showed surprising effects. The treatment is effective for all mice, half of them cured. The researchers hope to conduct clinical trials at St James ’s Hospital in Leeds in the UK within the next 18 months. If further trials are successful, this treatment will make a major leap forward in cancer treatment options.
Camera Bag,Camera And Lens Backpack,Camera Backpack,Camera Case
Ningbo Fineweather International Trade Co., Ltd. , https://www.nbfwsbag.com