China Educational Equipment Purchasing Network News: I learned from the Chinese Academy of Sciences that recently, the University of British Columbia in Canada has cooperated with the British Columbia Cancer Institute and the Center for Translational and Applied Genomics to develop a chip laboratory technology for silicone materials that allows Each cell is placed like a ball in a pinball machine, and then genetically tested. This "single cell gene analysis" technology makes genetic testing more sensitive and rapid, which is helpful for tumor analysis and clinical disease diagnosis. The Proceedings of the National Academy of Sciences published this week introduced the chip laboratory in detail.
This chip laboratory is about the size of a 9-volt battery and can analyze 300 cells simultaneously. The researchers devised a route to carry cells in liquid through microscopic pipes and small valves. When cells enter each small space one by one, their RNA will be extracted and copied for further analysis.
Standard genetic testing requires the use of a large number of cells in order to arrive at a "composite image" averaged by tens of millions of different cells, which will obscure the true properties of the cells and their interactions. "This is like using mixed fruit mousse to study why strawberries and raspberries are not the same." Said Carl Hansen, associate professor at the high-throughput biology center that led the study, and single-cell analysis is becoming the golden means of genetic research. Because even samples collected from the same tumor tissue contain normal cells and multiple cancer cell types, and single-cell analysis shows very small differences.
In addition, this chip laboratory integrates almost all the cell analysis processes. Not only can the cells be separated, but also the cells can be mixed with chemical reagents, and their genetic codes can be obtained by detecting the fluorescence emission during the reaction. All of this can be done on chip, not only simple to operate, but also cost-effective.
Coil Nails are a series of nails arranged in a circle connected by a piece of metal and loaded into a gun,It is often used on the roof and can finish one roll continuously, which is very efficient. the main coating methods of coil nails are smooth, screw, uncoated, galvanized.
Smooth shank nails are the most common and are often used for framing and general construction applications. They offer enough holding power for most everyday use.
Ring Shank
Ring shank nails offer superior holding power over smooth shank nails because the wood fills in the crevasse of the rings and also provide friction to help prevent the Nail from backing out over time. A ring shank nail is often used in softer types of wood where splitting is not an issue.
Screw Shank
A screw shank nail is generally used in hard woods to prevent the wood from splitting while the fastener is being driven. The fastener spins while being driven (like a screw) which creates a tight groove that makes the fastener less likely to back out.
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